We present the synthesis of hollow polymer microspheres that exhibit pH and redox sensitivity for controlled release of drugs in various conditions. Furthermore, magnetic and silver nanocrystals are chemically grown on the surface of the fabricated hollow polymer microspheres in order to expand their functionalities. Studies of their performance as magnetic hyperthermia agents, as well as surface-enhanced Raman active substrates was also carried out.

hollow polymer microspheres, distillation precipitation polymerization, controlled release, magnetic hyperthermia, surface-enhanced Raman spectroscopy