Κωδικός Εργασίας: EN0353 - Poster
A DETAILED MULTI-COMPARTMENTAL SKIN PENETRATION MODEL COUPLED TO A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR ASSESSING EXPOSURE TO CHEMICAL COMPOUNDS: THE CASE OF BISPHENOL A
D.A. Sarigiannis1,2, E.J. Handakas1, S.P. Karakitsios1
1 Τμήμα Χημικών Μηχανικών, Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης
2 ΕΚΕΤΑ/ΙΔΕΠ

Περιγραφή :

The study deals with the development of a multi-compartmental model of the skin for explicit description of penetration, absorption and potential metabolism of chemical compounds under different realistic exposure scenarios, coupled to a PBPK model.

Λέξεις Κλειδιά:

Skin model, PBPK, multi-route exposure